Chlorphenesin

Item No.: ZLEY®BIOCARE-CPH
CAS No.: 104-29-0
Appearance:  White to pale white crystalline powder
Recommended dosage:  0.1 - 0.3%
Solubility: Soluble in 65°C water or glycerol, propylene glycol
Property: Excellent antimicrobial & anti-fungal agent/ preservative in Cosmetics.
Description
Description:

Chlorophenesin is a preservative with fungistatic and bactericidal properties, it is widely used in cosmetics and personal care products. As a preservative, it prevents various products from encountering viscosity changes, PH changes, problems with demulsification, visible microbial growth, color changes, and terrible odors problems, etc. Chlorophenesin especially works on fungi, if combined with other preservatives, its function will be enhanced, the most important is to solve the toxic side effects caused by the residues of p-chlorophenol.  



Properties:

1. Dissolve in 65°C water or glycerol, propylene glycol.
2. Europe has allowed it as a preservative in cosmetics since 1996, and Japan and the United States also allowed to use it.
3. Compatible with most preservatives (including potassium sorbate, sodium benzoate, and methylisothiazolinone).
4.
Chlorophenesin is more effective for fungi. When used in combination with other preservatives, the antiseptic effect is enhanced.
 
Inspection items Technical index
Appearance White or off-white crystalline powder
Identification ldentification the solution shows two absorption max, at 228nm and 280nm
Clarity and colour of solution When freshly prepared, it is clear and colourless
Chloride NMT 0.05%
Melting point 78.0~82.0℃
LOD NMT 0.50%
ROI NMT 0.10%
Heavy metals NMT 10ppm
Residual Solvents (Methanol) NMT 0.05%
Related impurities
Unspecified impurities NMT 0.10%
Total Impurities NMT 0.50%
P-Chlorophenol NMT 10ppm
Arsenic NMT 3ppm
Purity (HPLC) NLT 99.0%


Instruction of Formulation Application:

1. Solubility:Water-soluble
2. pH:3.00~8.00
3. Dosage:0.1 - 0.3%(≤0.3%)
4. Working temperature:65-80℃
5. Aqueous phase: Compatible with polyols
6. Thickening system:No abnormal conditions are found
7. Combination proposal: 0.2% Chlorphenesin + 0.6% 1,2-Hexanediol 
0.2% Chlorphenesin + 0.6% Phenoxyethanol

8. Stability:
1)Heat-resistance:45℃, 90days
Standard of evaluation Odor Color Appearance
0.2%Chlorphenesin+99.8% Hexanediol Stable Stable Stable
Chlorphenesin Stable Stable Large particle solid appears
2)Cold-resistance:-18℃, 90days
Standard of evaluation Odor Color Appearance
0.2%Chlorphenesin+99.8% Hexanediol Stable Stable Stable
Chlorphenesin Stable Stable Small particle solid appears
3)Thermocycling:45℃/-18℃, 90days
Standard of evaluation Odor Color Appearance
0.2%Chlorphenesin+99.8% Hexanediol Stable Stable Stable
Chlorphenesin Stable Stable Stable
4)Light(Natural daylight), 60days
Standard of evaluation Odor Color Appearance
0.2%Chlorphenesin+99.8% Hexanediol Stable Stable Stable
Chlorphenesin Stable Stable Small particle solid appears
 
9. Application suggestion:Soluble in 65℃ water or glycerol, propylene glycol.
10. Storage recommendation:Store it in a cool and dry place. Shelf life is three years.
11. Incompatibility: Not found yet.



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